Blar i forfatter "Diaz Cánova, Diana Karina"

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    • Evolutionary genomics of cowpox virus and recombination in vitro between a naturally occurring cowpox virus and a vaccinia virus vectored influenza vaccine 

      Diaz Cánova, Diana Karina (Doctoral thesis; Doktorgradsavhandling, 2023-06-02)
      Modified vaccinia virus Ankara (MVA) is a promising orthopoxvirus (OPXV) vector vaccine candidate due to its host range restriction and good safety profile as a smallpox vaccine. It has been widely tested in clinical trials as a recombinant vector for vaccination against infectious diseases and cancers in humans and animals. Furthermore, it is being used as a smallpox and Mpox vaccine. However, the ...

    • Genomic Sequencing and Analysis of a Novel Human Cowpox Virus With Mosaic Sequences From North America and Old World Orthopoxvirus 

      Diaz Cánova, Diana Karina; Moens, Ugo; Brinkmann, Annika; Nitsche, Andreas; Okeke, malachy ifeanyi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-03)
      Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV isolated from an 18-year-old male living in Northern Norway. Restriction enzyme analysis and partial genome sequencing characterized this virus as an atypical cowpox virus (CPXV), which we named CPXV-No-H2. In this study, we determined the ...

    • Genomic Sequencing and Phylogenomics of Cowpox Virus 

      Diaz Cánova, Diana Karina; Mavian, Carla; Brinkmann, Annika; Nitsche, Andreas; Moens, Ugo; Okeke, Malachy Ifeanyi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)
      <i>Cowpox virus</i> (CPXV; genus <i>Orthopoxvirus</i>; family <i>Poxviridae</i>) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian region, five CPXVs isolated from cats and humans were collected and used in this study. We report the complete sequence of ...